Clinical trials are carefully designed research studies that answer specific questions about the safety and effectiveness of preventive techniques, medications, treatments, therapies or surgical techniques. Participation in a clinical trial is strictly voluntary.
Many studies that are developed and available are similar to treatments often referred to as the “gold standard.” Advancements in medicine may lead to improved outcomes through improved results, less discomfort, less time involved in treatment, lower cost, and/or improved safety. At Urology Associates, we are very selective about studies that we choose to offer to our patients. Please read further to see what is currently offered and contact our office with any questions.
Urology Associates is enrolling patients for clinical trials for benign prostatic hyperplasia (BPH), urologic cancers, stress incontinence, among others, in order to help our patients live longer, healthier lives.
Am I eligible?
Many studies have strict enrollment criteria. The list of inclusion and exclusion criteria are different for each study. Our office can easily assess whether a patient is eligible for a particular study.
Deciding whether or not to participate in a urology clinical trial is a very important choice that should be carefully considered and thoroughly discussed between a patient and his or her doctor.
CONQUER – bladder cancer study
The purpose of this study is to evaluate the Time to Recurrence in patients with low- to intermediate-risk non-muscle invasive bladder cancer (NMIBC) who receive either 8 mg Qapzola or placebo post transurethral resection of bladder tumor (TURBT).Eligibility Criteria
- Patient has diagnosis of low to intermediate risk NMIBC.
- Patient is at least 18 years of age and <90 years of age.
- Patient has high risk NMIBC or bladder cancer that is muscle invasive or positive for metastasis.
- Patient has received any previous intravesical therapy for bladder cancer – chemotherapy, immunotherapy (NO BCG!).
- Patient has any unstable or uncontrolled medical condition that would make it unsafe to undergo a TURBT.
QUILT Study – bladder cancer study
The purpose of this study is to assess the antitumor activity of intravesical BCG in combination with ALT-803 immunotherapy protein complex in patients with BCG unresponsive high-grade NMIBC as determined by the disease response rating using cystoscopy, bladder biopsy and urine cytology.Eligibility Criteria
- Male or female patients 18 years of age or older.
- Histologic confirmation of NMIBC of the transitional cell carcinoma high-grade subtype.
- BCG unresponsive disease as defined as persistent high grade disease or recurrence within 6 months of receiving at least 2 courses of BCG (1 induction course and 1 maintenance course).
- Recurrence > 6 months after last BCG instillation.
- Evidence of muscle-invasion or regional and/or distant metastatic bladder cancer.
- Symptomatic CHF, severe/unstable angina pectoris, or myocardial infarction within 6 months prior to study entry.
PREVAIL Study – Non-Interventional Study for Patients with Locally Advanced/Unresectable or Metastatic Bladder Cancer
The purpose of this study is to assess the prevalence of PD-L1 expression in the first-line setting of locally advanced/unresectale or metastatic urothelial carcinoma.Eligibility Criteria
- Patients age ≥ 18 years or older.
- Patients with histologically confirmed diagnosis of UC and confirmed advanced UC prior to or during 1L therapy.
- Patients with available tumor tissue sample that was collected as part of standard of care and time prior to 1L therapy.
- Patients with history of non-urothelial active malignancy that completed therapy within 2 years from study enrollment.
- Patients concurrently enrolled in other clinical trials that prohibit their participation in a non-interventional study.